The role of calcium in drug action michael denborough home worldcat home about worldcat help search search for library items search for lists search for contacts search for a library create lists bibliographies and reviews or search worldcat find items in libraries near you . The synergistic effect of serum on the drug combination of salicylhydroxamic acid plus glycerol which is active against trypanosoma brucei is due to diffusible calcium ions the synergistic activity can be removed by dialysis of the serum or by addition of calcium chelating agents a buffer containing calcium can mimic the synergistic activity of serum. You can read role of calcium in drug action online using button below 1 calcium in biology calcium ions ca 2 contribute to the physiology and biochemistry of organisms and the cellthey play an important role in signal transduction pathways where they act as a second messenger in. Role of calcium in trypanocidal drug action clarkson ab jr amole bo the synergistic effect of serum on the drug combination of salicylhydroxamic acid plus glycerol which is active against trypanosoma brucei is due to diffusible calcium ions. Calcium channel blockers inhibit entry of calcium into cells another dimension of drug action which only recently has been taken into account refers to the subcellular localization of transmembrane receptors in this context a receptor can be functionally localized at the plasma membrane and or the cell nucleus wherein it exerts
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