The aim of the present study was to evaluate the effect of chronic treatment with nadolol on liver blood flow and liver function nadolol a non cardioselective beta adrenoceptor blocker has been reported to be as powerful as propranolol in decreasing portal pressure. Chronic administration of nadolol has been reported to reduce blood pressure either without or with a concomitant fall of renal blood flow we therefore studied the effects of nadolol 80 mg once daily on ambulatory blood pressure renal and systemic haemodynamics in patients with mild to moderate essential hypertension. Br j clin pharmac 1986 21 713 719 effect of nadolol on liver haemodynamics and function in patients with cirrhosis c merkel d sacerdoti g f finucci r zuin g bazzerla m bolognesi a gatta department of clinical medicine university of padua padua italy p adrenoceptor blockers used in the medical management of portal hypertension decrease liver blood flow. Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applied. Nadolol at a dose reducing heart rate by 25 in 15 cirrhotic patients with portal hypertension the following parameterswere determined hepatic venouspressure gradient hepaticbloodflow galactose eliminatingcapacity aminopyrine metabolicactivity icg
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