Chromaffin cells in the adrenal medulla are specialized for the synthesis storage and secretion of catecholamines these cells are innervated by preganglionic sympathetic neurons in the splanchnic nerves and because of their unique blood supply are exposed to unusually high concentrations of . Understanding mechanisms that influence catecholamine biosynthesis storage secretion and degradation in the adrenal medulla of young shrs may give clues as to which processes are dysregulated early in the development of hypertension before full manifestation of the disease and may shed light on factors that mediate disease susceptibility. Synthesis storage and secretion of adrenal medullary hormones physiology and pathophysiology james b young department of medicine northwestern university medical school chicago illinois role of adrenal catecholamines in regulation of adrenal cortical function. Secretion of catecholamines from the adrenal gland by various agents s m kirpekar et al ouabain potentiates catecholamine secretion induced by splanchnic nerve stimulation acetylcholine and excess potassium in perfused adrenal glands of guinea pig y nakazato et al reduction in calcium concentration induces exocytotic secretion of . Chromaffin cells in the adrenal medulla are specialized for the synthesis storage and secretion of catecholamines these cells are innervated by preganglionic sympathetic neurons in the
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