Pharmacokinetics and anaesthesia fred roberts mb chb frca 1consultant anaesthetist and honorary clinical lecturerdepartment of anaesthesiaroyal devon and exeter hospital wonfordbarrack road exeter ex2 5dwuktel 44 01392 402474e mail coolfredbtinternetcom. Anesthesia is a combination of unconsciousness amnesia and analgesia expressed in sleeping patients by limited reaction to noxious stimulations it is achieved by several classes of drugs acting mainly on central nervous system compared to other therapeutic families the anesthetic drugs . Pharmacokinetics is a system of mathematical modelling of in vivo processes particularly distribution and elimination it is by definition a model and the one most often used to illustrate the pharmacokinetics of propofol for example is the three compartment model. The pharmacology of anesthesia is extremely complex this lesson will give you a quick first look at its many different aspects using clearly defined terminology. Pharmacology for anaesthesia and intensive care third edition the third edition of this market leading book hasbeen thoroughly updated and expandedwith additional contributions fromexpertsin the eld to include all new drugs available to the anaesthetist andintensivecare specialist basic
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