Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applied. Ten female patients with recurrent cutaneous malignant melanoma mm confined to the lower limb were treated with 4 hydroxyanisole 4ha infused intra arterially 10 g of 4ha was infused twice per day up to a maximum dose of 80 g 4ha infusion caused significant alterations in liver function which precluded completion of the treatment regimen in all but two patients. Intra arterial4 hydroxyanisole chemotherapy for recurrent malignant melanoma 209 chemical profile including liver function tests a methaemoglobin assay and urine analysis. Research into the causes prevention and treatment of melanoma is being done in medical centers throughout the world causes prevention and early detection sunlight and ultraviolet uv radiation recent studies suggest there may be 2 main ways that uv exposure is linked to melanoma but there is likely some overlap
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