Tuberculosis tb is a serious public health problem worldwide its situation is worsened by the presence of multidrug resistant mdr strains of mycobacterium tuberculosis the causative agent of the diseasein recent years even more serious forms of drug resistance have been reported. We found high prevalence rates of multidrug resistant tuberculosis among retreatment patients 711 and persons with new cases 80 in angola these findings are of concern but should be interpreted with caution a national drug resistance survey is urgently needed to determine the actual prevalence of multidrug resistant tuberculosis in angola. Drug resistance in mycobacterium tuberculosis from microbewiki the student edited microbiology resource jump to navigation search this student page has not been curated tuberculosis tb is a potentially deadly disease caused by pathogenic bacteria usually mycobacterium tuberculosis. Detection of all forms of drug resistance in tb is a key factor to reduce and contain the spread of these resistant strains a better knowledge of the mechanisms of action of anti tb drugs and the development of drug resistance will allow identifying new drug targets and better ways to detect drug resistance. Fig 1 overview of the mycobacterial cell wall and resistance determinants natural drug resistance in mycobacteria is conferred by their highly lipophilic cell wall and the various mechanisms that control the cell wall content a low number of porins broad range of efflux pumps active biotransformation by cytosolic enzymes and inducible resistance mechanisms see text for details
How it works:
1. Register a Free 1 month Trial Account.
2. Download as many books as you like ( Personal use )
3. No Commitment. Cancel anytime.
4. Join Over 100.000 Happy Readers.
5. That's it. What you waiting for? Sign Up and Get Your Books.