Drug induced hepatic injury 2e2nd edition laboratory techniques in biochemistry and molecular biology by b hc stricker b hch stricker hardcover 550 pages published 1992 by elsevier isbn 13 978 0 444 81303 9 isbn 0 444 81303 9. Molecular mechanisms underlying chemical liver injury volume 14 xinsheng gu jose e manautou journal of biochemistry and molecular biology 38 259 265 97 zhang y et al 2010 2010 drug induced liver injury past present and future pharmacogenomics 11 607 611. Drug induced liver injury is the leading cause of acute liver failure and transplantation in western countries the detection of subtle mechanisms that lead to potential drug hepatotoxicity is of key importance and remains a major challenge in clinical practice the frequent involvement of the liver . Biochemistry molecular biology 2012 abstract idiosyncratic drug induced liver injury is a type of adverse reaction that occurs in a small fraction of patients during drug therapy amiodarone amd is a class iii he taught me all kinds of lab techniques especially in animal studies dr wei zou is the person i asked the most. Liver injury due to prescription and nonprescription medications is a growing medical scientific and public health problem worldwide the estimated annual incidence rate of drug induced liver injury dili is 139 240 per 100000 inhabitants dili is one of the leading causes of acute liver failure in the us
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