Stephens detection of new adverse drug reactions provides comprehensive and up to date coverage of material fundamentally important to all those active in the field whether they work in the pharmaceutical industry drug regulatory authorities or in academiakingbook73s medical ebook and video collection. Adverse drug reactions have a history that goes back thousands of years however modern interest which started in the 1930s dates largely from the period 1975 1985 marked at that time by a dramatic increase in the numbers of publications in whose titles or abstracts the words adverse drug reactions appeared figure 1. Detection of new adverse drug reactions is fundamental to the protection of patients from harm that may occur as a result of medication this book explores the methods used to investigate new adverse drug reactions discussing all elements from the scientific background and animal toxicology through to worldwide regulatory and ethical issues. Classification of adverse drug reactions 92 risk factors for type a adverse reactions 93 risk factors for type b adverse reactions 101 detection of adverse drug reactions 106 stephens detection of new adverse drug reactions fifth edition edited by john talbot and patrick waller 2004 john wiley sons ltd isbn 0 470 84552 x. Stephens detection of new adverse drug reactions talbot j isbn 13 9780470986349 table of contents foreword preface to the sixth edition list of contributors acknowledgements 1 adverse drug reactions history terminology classification causality frequency preventability jeffrey k aronson 11 introduction 12 defining pharmacovigilance
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