What causes cardiac toxicity there are many possible causes of cardiac toxicity in cancer patients cardiac toxicity may be caused by radiation to the chest and some chemotherapy drugs the most well known cause of cardiac toxicity is the chemotherapy drug doxorubicin adriamycinr doxorubicin is a type of chemotherapy drug called an . Cardiac drugs such as cardiac glycosides blockers calcium antagonists and antiarrhythmics are used to treat a variety of heart conditions such as congestive heart failure high blood . Sj liu rb melchert in comprehensive toxicology 2010 cardiotoxicity has often been observed with the advent of pharmaceuticals for conditions such as cancer and characterized by abnormality of cardiac electrical activity and contractile dysfunction ultimately leading to heart failure finding and understanding the primary cause of cardiotoxicity would improve pharmaceutical development
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