An adverse drug reaction adr is an unwanted unde adverse drug reactions may cause patients to lose confi dence in or have negative emotions toward their physicians and seek self treatment options which may consequently detection assessment understanding and prevention of adrs pharmacists play a vital role in every step of the. An adverse drug reaction adr is an injury caused by taking medication adrs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs the meaning of this expression differs from the meaning of side effect as this last expression might also imply that the effects can be beneficial . Causality assessment of adrs is a method used for estimating the strength of relationship between drugs exposure and occurrence of adverse reactions causality assessment of adrs may be undertaken by clinicians academics the pharmaceutical industry and regulators and in different settings including clinical trials 188 191 at an . Adverse drug reaction causality assessment srinivasan r and ramya g pes college of pharmacy department of pharmacy practice 50 ft road hanumanth nager bangalore karnataka india corresponding author cdmseenagmailcom introduction adverse drug reactions adrs are considered as one among the leading causes of morbidity and mortality1. Assessment of adverse drug reactions symptomatology of adverse drug reactions radiocontrast media for example do cause anaphylactoid immediate type reactions but in some patients delayed reactions after 6 12 h like angioedema dyspnea ede cardiovascular reactions gastrointestinal complaints headache and flu like symptoms may occur
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