Clinical benefits of correcting renal anemia the availability of recombinant human erythropoietin rhuepo has greatly changed the management of anemia in patients with ckd allowing hemoglobin levels to be effectively moved towards higher values. Correction of the anemia of end stage renal disease with recombinant human erythropoietin results of a combined phase i and ii clinical trial n engl j med 1987 jan 8 316 273 78. The availability of recombinant human erythropoietin rhuepo has greatly changed the management of anemia in ckd patients besides improving hemoglobin levels rhuepo therapy has been demonstrated to significantly improve quality of life and decrease morbidity and mortality in patients with ckd. Human recombinant erythropoietin in the treatment of anemia of patients with chronic renal failure or 4 chronic kidney disease and do not receive dialysis more than 320000 have stage 5 disease including patients as a treatment of anemia in two groups of patients having chronic renal disease group 1 . Abstract the administration of recombinant human erythropoietin r huepo for treatment of anemia in dogs with renal failure is practical in most of veterinary hospitals but there is a variation in clinical use among them
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